What is EN ISO 6768:2021?

EN ISO 6768:2021 is a technical standard that provides guidelines for the calculation and expression of particle size distribution in powders. It was developed by the International Organization for Standardization (ISO) to ensure consistency and accuracy in determining particle sizes. This standard is widely used in various industries, including pharmaceuticals, chemicals, and food processing.

The Importance of Particle Size Distribution

Particle size distribution plays a crucial role in many applications. It affects the physical properties and performance of powders, such as flowability, dissolution rate, and packing density. By understanding the particle size distribution, manufacturers can optimize their processes, improve product quality, and meet regulatory requirements.

Calculation Methodologies

EN ISO 6768:2021 provides several methodologies for calculating particle size distribution. One commonly used technique is laser diffraction, which measures the scattering pattern produced when a laser beam passes through the sample. Another method is sedimentation, where particles settle in a liquid under the influence of gravity, and their settling velocity is used to determine their size. Other techniques include microscopy, sieving, and electrical sensing zone.

Expressing Particle Size Distribution

The standard also defines how to express particle size distribution accurately. The most common representation is the cumulative distribution curve, which shows the percentage of particles below a certain size. This curve can be plotted on logarithmic or linear scales, depending on the desired level of detail. Additionally, the standard recommends reporting specific parameters such as D10, D50, and D90, which represent the particle sizes below which 10%, 50%, and 90% of the particles fall, respectively.

In conclusion, EN ISO 6768:2021 is an essential standard for accurately measuring and expressing particle size distribution in powders. By following its guidelines, manufacturers can ensure consistent results, optimize their processes, and produce high-quality products. Understanding particle size distribution is crucial for a wide range of industries, as it directly impacts product performance and regulatory compliance.